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RAD51 and MRE11 dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

In higher eukaryotes the dynamics of replisome components during fork collapse and restart are poorly understood. Here, we reconstituted replication fork collapse and restart by inducing single-strand DNA (ssDNA) lesions that create a double-strand break (DSB) in one of the replicated sister chromat...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Hashimoto, Yoshitami, Puddu, Fabio, Costanzo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306020/
https://ncbi.nlm.nih.gov/pubmed/22139015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2177
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