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ATR activation and replication fork restart are defective in FANCM-deficient cells
Fanconi anaemia is a chromosomal instability disorder associated with cancer predisposition and bone marrow failure. Among the 13 identified FA gene products only one, the DNA translocase FANCM, has homologues in lower organisms, suggesting a conserved function in DNA metabolism. However, a precise...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829160/ https://ncbi.nlm.nih.gov/pubmed/20057355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.385 |
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