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Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
We investigated the mechanisms by which inhibitors of prostaglandin G/H synthase-2 (PGHS-2; known colloquially as COX-2) increase the incidence of myocardial infarction and stroke. These inhibitors are believed to exert both their beneficial and their adverse effects by suppression of PGHS-2–derived...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1435722/ https://ncbi.nlm.nih.gov/pubmed/16614756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27540 |
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