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Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

We investigated the mechanisms by which inhibitors of prostaglandin G/H synthase-2 (PGHS-2; known colloquially as COX-2) increase the incidence of myocardial infarction and stroke. These inhibitors are believed to exert both their beneficial and their adverse effects by suppression of PGHS-2–derived...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Cheng, Yan, Wang, Miao, Yu, Ying, Lawson, John, Funk, Colin D., FitzGerald, Garret A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435722/
https://ncbi.nlm.nih.gov/pubmed/16614756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27540
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