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Cardiovascular Consequences of Prostanoid I Receptor Deletion in Microsomal Prostaglandin E Synthase-1 Deficient Hyperlipidemic Mice

BACKGROUND: Inhibitors of cyclooxygenase-2 (COX-2) alleviate pain and reduce fever and inflammation by suppressing biosynthesis of prostacyclin (PGI(2)) and prostaglandin E(2) (PGE(2)). However, suppression of these PGs, particularly PGI(2), by COX-2 inhibition or deletion of its I prostanoid (Ip) r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Circulation
Päätekijät: Tang, Soon Yew, Monslow, James, Grant, Gregory R., Todd, Leslie, Pawelzik, Sven-Christian, Chen, Lihong, Lawson, John, Puré, Ellen, FitzGerald, Garret A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963279/
https://ncbi.nlm.nih.gov/pubmed/27440004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.022308
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