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Cardiovascular Consequences of Prostanoid I Receptor Deletion in Microsomal Prostaglandin E Synthase-1 Deficient Hyperlipidemic Mice
BACKGROUND: Inhibitors of cyclooxygenase-2 (COX-2) alleviate pain and reduce fever and inflammation by suppressing biosynthesis of prostacyclin (PGI(2)) and prostaglandin E(2) (PGE(2)). However, suppression of these PGs, particularly PGI(2), by COX-2 inhibition or deletion of its I prostanoid (Ip) r...
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| Publicado no: | Circulation |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963279/ https://ncbi.nlm.nih.gov/pubmed/27440004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.022308 |
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