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Telomere Position Effect and Silencing of Transgenes near Telomeres in the Mouse
Reversible transcriptional silencing of genes located near telomeres, termed the telomere position effect (TPE), is well characterized in Saccharomyces cerevisiae. TPE has also been observed in human tumor cell lines, but its function remains unknown. To investigate TPE in normal mammalian cells, we...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430234/ https://ncbi.nlm.nih.gov/pubmed/16479005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1865-1878.2006 |
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