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Molecular beacons with intrinsically fluorescent nucleotides

We report the design, synthesis and characterization of a novel molecular beacon (MB-FB) which uses the fluorescent bases (FB) 2-aminopurine (AP) and pyrrolo-dC (P-dC) as fluorophores. Because the quantum yield of these FB depend on hybridization with complementary target, the fluorescent properties...

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Main Authors: Martí, Angel A., Jockusch, Steffen, Li, Zengmin, Ju, Jingyue, Turro, Nicholas J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428799/
https://ncbi.nlm.nih.gov/pubmed/16595796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl134
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