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Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Amyloid β-protein (Aβ) is linked to neuronal injury and death in Alzheimer's disease (AD). Of particular relevance for elucidating the role of Aβ in AD is new evidence that oligomeric forms of Aβ are potent neurotoxins that play a major role in neurodegeneration and the strong association of th...

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Autori principali: Bitan, Gal, Kirkitadze, Marina D., Lomakin, Aleksey, Vollers, Sabrina S., Benedek, George B., Teplow, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC140968/
https://ncbi.nlm.nih.gov/pubmed/12506200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222681699
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