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Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Amyloid β-protein (Aβ) is linked to neuronal injury and death in Alzheimer's disease (AD). Of particular relevance for elucidating the role of Aβ in AD is new evidence that oligomeric forms of Aβ are potent neurotoxins that play a major role in neurodegeneration and the strong association of the 42-...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Bitan, Gal, Kirkitadze, Marina D., Lomakin, Aleksey, Vollers, Sabrina S., Benedek, George B., Teplow, David B.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12506200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222681699
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