Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Amyloid β-protein (Aβ) is linked to neuronal injury and death in Alzheimer's disease (AD). Of particular relevance for elucidating the role of Aβ in AD is new evidence that oligomeric forms of Aβ are potent neurotoxins that play a major role in neurodegeneration and the strong association of the 42-...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bitan, Gal, Kirkitadze, Marina D., Lomakin, Aleksey, Vollers, Sabrina S., Benedek, George B., Teplow, David B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12506200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222681699
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