β-Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of β2 adrenergic receptor Gαs signaling in 3T3-L1 adipocytes
β-Arrestin 1 is required for internalization and mitogen-activated protein (MAP) kinase activation by the β2 adrenergic receptor (β2AR). Our previous studies have shown that chronic insulin treatment down-regulates cellular β-arrestin 1 levels, leading to a marked impairment in G protein-coupled rec...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0235674100 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|