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Properly Folded Nonstructural Polyprotein Directs the Semliki Forest Virus Replication Complex to the Endosomal Compartment

The late RNA synthesis in alphavirus-infected cells, generating plus-strand RNAs, takes place on cytoplasmic vacuoles (CPVs), which are modified endosomes and lysosomes. The cytosolic surface of CPVs consists of regular membrane invaginations or spherules, which are the sites of RNA synthesis (P. Ku...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Salonen, Anne, Vasiljeva, Lidia, Merits, Andres, Magden, Julia, Jokitalo, Eija, Kääriäinen, Leevi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.3.1691-1702.2003
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