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Properly Folded Nonstructural Polyprotein Directs the Semliki Forest Virus Replication Complex to the Endosomal Compartment

The late RNA synthesis in alphavirus-infected cells, generating plus-strand RNAs, takes place on cytoplasmic vacuoles (CPVs), which are modified endosomes and lysosomes. The cytosolic surface of CPVs consists of regular membrane invaginations or spherules, which are the sites of RNA synthesis (P. Ku...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Salonen, Anne, Vasiljeva, Lidia, Merits, Andres, Magden, Julia, Jokitalo, Eija, Kääriäinen, Leevi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.3.1691-1702.2003
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