Properly Folded Nonstructural Polyprotein Directs the Semliki Forest Virus Replication Complex to the Endosomal Compartment

The late RNA synthesis in alphavirus-infected cells, generating plus-strand RNAs, takes place on cytoplasmic vacuoles (CPVs), which are modified endosomes and lysosomes. The cytosolic surface of CPVs consists of regular membrane invaginations or spherules, which are the sites of RNA synthesis (P. Ku...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Salonen, Anne, Vasiljeva, Lidia, Merits, Andres, Magden, Julia, Jokitalo, Eija, Kääriäinen, Leevi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.3.1691-1702.2003
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