A Truncated Form of Nef Selected during Pathogenic Reversion of Simian Immunodeficiency Virus SIVmac239Δnef Increases Viral Replication

The live, attenuated vaccine simian immunodeficiency virus SIVmac239Δnef efficiently protects rhesus macaques against infection with wild-type SIVmac but occasionally causes CD4(+) T-cell depletion and progression to simian AIDS (SAIDS). Virus recovered from a vaccinated macaque (Rh1490) that progre...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Chakrabarti, Lisa A., Metzner, Karin J., Ivanovic, Tijana, Cheng, Hua, Louis-Virelizier, Jean, Connor, Ruth I., Cheng-Mayer, Cecilia
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Pathogenesis and Immunity
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.1245-1256.2003
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