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Ligand-induced estrogen receptor α degradation by the proteasome: new actors?

In this perspective we consider new aspects of ligand-induced estrogen receptor α (ERα) degradation. What are the possible roles of CSN5/Jab1 and the CSN complex in this process? We compare hormone (estrogen) or pure antagonist (fulvestrant) induced degradation of ERα and review the effects of kinas...

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Detalhes bibliográficos
Main Authors: Calligé, Mathilde, Richard-Foy, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: The Nuclear Receptor Signaling Atlas 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402212/
https://ncbi.nlm.nih.gov/pubmed/16604167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04004
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