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Estrogen Receptor-α Hinge-Region Lysines 302 and 303 Regulate Receptor Degradation by the Proteasome
Cellular levels of estrogen receptor-α (ERα) protein are regulated primarily by the ubiquitin-proteasome pathway. Dynamic interactions between ERα and the protein degradation machinery facilitate the down-regulation process by targeting receptor lysine residues for polyubiquitination. To date, the l...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453605/ https://ncbi.nlm.nih.gov/pubmed/18388150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0449 |
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