A carregar...
CSN5/Jab1 Is Involved in Ligand-Dependent Degradation of Estrogen Receptor α by the Proteasome
Here, we show that estrogen receptor α (ERα) coimmunoprecipitates with CSN5/Jab1, a subunit of the COP9 signalosome (CSN), and that overexpression of CSN5/Jab1 causes an increase in ligand-induced ERα degradation. Inhibition of either the kinase activity associated with the CSN complex by curcumin o...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140630/ https://ncbi.nlm.nih.gov/pubmed/15899841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4349-4358.2005 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|