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Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation
[Image: see text] A series of (E)-3-(4-((2,4-bis(trifluoromethyl)benzyl)oxy)-3-methoxyphenyl)-2-cyanoacrylamide derivatives were designed and synthesized as new estrogen-related receptor α (ERRα) degraders based on the proteolysis targeting chimera (PROTAC) concept. One of the representative compoun...
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| Pubblicato in: | ACS Med Chem Lett |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2019
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512006/ https://ncbi.nlm.nih.gov/pubmed/31097997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00025 |
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