Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective

Mechanistic insights into aggrephagy, a selective basal autophagy process to clear misfolded protein aggregates, are lacking. Here, we report and describe the role of Estrogen Related Receptor α (ERRα, HUGO Gene Nomenclature ESRRA), new molecular player of aggrephagy, in keeping autophagy flux in ch...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Suresh, S. N., Chavalmane, Aravinda K., Pillai, Malini, Ammanathan, Veena, Vidyadhara, D. J., Yarreiphang, Haorei, Rai, Shashank, Paul, Abhik, Clement, James P., Alladi, Phalguni A., Manjithaya, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900053/
https://ncbi.nlm.nih.gov/pubmed/29686608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00109
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