טוען...
Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen
Inactivation of the retinoblastoma (Rb) tumor suppressor by Simian virus 40 (SV40) large T antigen is one of the central features of tumorigenesis induced by SV40. Both the N-terminal J domain and the LxCxE motif of large T antigen are required for inactivation of Rb. The crystal structure of the N-...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2001
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140208/ https://ncbi.nlm.nih.gov/pubmed/11226179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.1.295 |
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