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Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen.

We have attempted to identify human topoisomerase I-binding proteins in order to gain information regarding the cellular roles of this protein and the cytotoxic mechanisms of the anticancer drug camptothecin, which specifically targets topoisomerase I. In the course of this work we identified an int...

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Bibliographic Details
Main Authors: Haluska, P, Saleem, A, Edwards, T K, Rubin, E H
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC147454/
https://ncbi.nlm.nih.gov/pubmed/9512561
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