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Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen.

We have attempted to identify human topoisomerase I-binding proteins in order to gain information regarding the cellular roles of this protein and the cytotoxic mechanisms of the anticancer drug camptothecin, which specifically targets topoisomerase I. In the course of this work we identified an int...

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Autores principales: Haluska, P, Saleem, A, Edwards, T K, Rubin, E H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC147454/
https://ncbi.nlm.nih.gov/pubmed/9512561
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