Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen

Inactivation of the retinoblastoma (Rb) tumor suppressor by Simian virus 40 (SV40) large T antigen is one of the central features of tumorigenesis induced by SV40. Both the N-terminal J domain and the LxCxE motif of large T antigen are required for inactivation of Rb. The crystal structure of the N-...

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Bibliografski detalji

Izdano u:	EMBO J
Glavni autori:	Kim, Hye-Yeon, Ahn, Byung-Yoon, Cho, Yunje
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2001
Teme:	Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.1.295
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