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Optimization of trans-splicing ribozyme efficiency and specificity by in vivo genetic selection

Trans-splicing ribozymes are RNA-based catalysts capable of splicing RNA sequences from one transcript specifically into a separate target transcript. In doing so, a chimeric mRNA can be produced, and new gene activities triggered in living cells dependent on the presence of the target mRNA. Based o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ayre, Brian G., Köhler, Uwe, Turgeon, Robert, Haseloff, Jim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC140090/
https://ncbi.nlm.nih.gov/pubmed/12490732
Tagiau: Ychwanegu Tag
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