Homologous Recombination Resolution Defect in Werner Syndrome

Werner syndrome (WRN) is an uncommon autosomal recessive disease whose phenotype includes features of premature aging, genetic instability, and an elevated risk of cancer. We used three different experimental strategies to show that WRN cellular phenotypes of limited cell division potential, DNA dam...

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Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Saintigny, Yannick, Makienko, Kate, Swanson, Cristina, Emond, Mary J., Monnat, Jr., Raymond J.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2002
Sujets:	DNA Dynamics and Chromosome Structure
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.6971-6978.2002
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