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Homologous Recombination Resolution Defect in Werner Syndrome

Werner syndrome (WRN) is an uncommon autosomal recessive disease whose phenotype includes features of premature aging, genetic instability, and an elevated risk of cancer. We used three different experimental strategies to show that WRN cellular phenotypes of limited cell division potential, DNA dam...

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Publicado no:Mol Cell Biol
Principais autores: Saintigny, Yannick, Makienko, Kate, Swanson, Cristina, Emond, Mary J., Monnat, Jr., Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.6971-6978.2002
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