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Homologous Recombination Resolution Defect in Werner Syndrome

Werner syndrome (WRN) is an uncommon autosomal recessive disease whose phenotype includes features of premature aging, genetic instability, and an elevated risk of cancer. We used three different experimental strategies to show that WRN cellular phenotypes of limited cell division potential, DNA dam...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Mol Cell Biol
Ngā kaituhi matua: Saintigny, Yannick, Makienko, Kate, Swanson, Cristina, Emond, Mary J., Monnat, Jr., Raymond J.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis 2002
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.6971-6978.2002
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