Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice

Thymidine phosphorylase (TP) regulates intracellular and plasma thymidine levels. TP deficiency is hypothesized to (i) increase levels of thymidine in plasma, (ii) lead to mitochondrial DNA alterations, and (iii) cause mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). In order to elucid...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Haraguchi, Misako, Tsujimoto, Hiroaki, Fukushima, Masakazu, Higuchi, Itsuro, Kuribayashi, Hideto, Utsumi, Hideo, Nakayama, Atsuo, Hashizume, Yoshio, Hirato, Junko, Yoshida, Hiroki, Hara, Hiromitsu, Hamano, Shinjiro, Kawaguchi, Hiroaki, Furukawa, Tatsuhiko, Miyazono, Kohei, Ishikawa, Fuyuki, Toyoshima, Hideo, Kaname, Tadashi, Komatsu, Masaharu, Chen, Zhe-Sheng, Gotanda, Takenari, Tachiwada, Tokushi, Sumizawa, Tomoyuki, Miyadera, Kazutaka, Osame, Mitsuhiro, Noda, Tetsuo, Yamada, Yuji, Akiyama, Shin-ichi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139774/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12077348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.14.5212-5221.2002
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!