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Transforming growth factor-β and breast cancer: Cell cycle arrest by transforming growth factor-β and its disruption in cancer

Altered responsiveness to extracellular signals and cell cycle dysregulation are hallmarks of cancer. The cell cycle is governed by cyclin-dependent kinases (cdks) that integrate mitogenic and growth inhibitory signals. Transforming growth factor (TGF)-β mediates G(1) cell cycle arrest by inducing o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Donovan, Jeffrey, Slingerland, Joyce
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC139433/
https://ncbi.nlm.nih.gov/pubmed/11250701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr43
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