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Transforming growth factor-β and breast cancer: Cell cycle arrest by transforming growth factor-β and its disruption in cancer
Altered responsiveness to extracellular signals and cell cycle dysregulation are hallmarks of cancer. The cell cycle is governed by cyclin-dependent kinases (cdks) that integrate mitogenic and growth inhibitory signals. Transforming growth factor (TGF)-β mediates G(1) cell cycle arrest by inducing o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2000
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139433/ https://ncbi.nlm.nih.gov/pubmed/11250701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr43 |
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