Llwytho...

Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

p27 is a key regulator of progression from G1 to S phase. Although the gene encoding p27 is rarely mutated in human cancers, p27 is functionally inactivated in a majority of human cancers through accelerated p27 proteolysis, through sequestration by cyclin D–cyclin-dependent kinase complexes and by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alkarain, Angel, Slingerland, Joyce
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC314445/
https://ncbi.nlm.nih.gov/pubmed/14680481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr722
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