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The role of chromosomal instability in tumor initiation

Chromosomal instability (CIN) is a defining characteristic of most human cancers. Mutation of CIN genes increases the probability that whole chromosomes or large fractions of chromosomes are gained or lost during cell division. The consequence of CIN is an imbalance in the number of chromosomes per...

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Bibliografski detalji
Glavni autori: Nowak, Martin A., Komarova, Natalia L., Sengupta, Anirvan, Jallepalli, Prasad V., Shih, Ie-Ming, Vogelstein, Bert, Lengauer, Christoph
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC138593/
https://ncbi.nlm.nih.gov/pubmed/12446840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202617399
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