Lanean...
Gα(q) binds to p110α/p85α phosphoinositide 3-kinase and displaces Ras
Several studies have reported that activation of G(q)-coupled receptors inhibits PI3K (phosphoinositide 3-kinase) signalling. In the present study, we used purified proteins to demonstrate that Gα(q) directly inhibits p110α/p85α PI3K in a GTP-dependent manner. Activated Gα(q) binds to the p110α/p85α...
Gorde:
| Egile Nagusiak: | , , , , |
|---|---|
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Portland Press Ltd.
2006
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383705/ https://ncbi.nlm.nih.gov/pubmed/16268778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051493 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|