5-Lipoxygenase-activating protein homodimer in human neutrophils: evidence for a role in leukotriene biosynthesis

FLAP (5-lipoxygenase-activating protein) is a nuclear transmembrane protein involved in the biosynthesis of LTs (leukotrienes) and other 5-LO (5-lipoxygenase) products. However, little is known about its mechanism of action. In the present study, using cross-linkers, we demonstrate that FLAP is pres...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Plante, Hendrick, Picard, Serge, Mancini, Joseph, Borgeat, Pierre
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2005
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383679/
https://ncbi.nlm.nih.gov/pubmed/16144515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060669
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