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Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H(2) receptor and cAMP

1. Histamine is generally regarded as a pro-inflammatory mediator in diseases such as allergy and asthma. A growing number of studies, however, suggest that this autacoid is also involved in the downregulation of human polymorphonuclear leukocyte (PMN) functions and inflammatory responses through ac...

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Main Authors: Flamand, Nicolas, Plante, Hendrick, Picard, Serge, Laviolette, Michel, Borgeat, Pierre
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574237/
https://ncbi.nlm.nih.gov/pubmed/14744809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705654
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