Activation of the human neutrophil 5-lipoxygenase by leukotriene B4.

1. In the present study, we demonstrate that leukotriene B4 (LTB4) has the ability to activate the human neutrophil 5-lipoxygenase (5-LO). 2. Stimulation of neutrophils with 30 nM 14,15-dideuterio-LTB4 (D2-LTB4) failed to induce the synthesis of LTB4 from endogenous arachidonic acid (AA), but stimul...

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Bibliografske podrobnosti
Main Authors: McDonald, P. P., McColl, S. R., Naccache, P. H., Borgeat, P.
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907591/
https://ncbi.nlm.nih.gov/pubmed/1330161
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