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Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells

The aim of the present investigation was to elucidate further the importance of p38 MAPK (mitogen-activated protein kinase) in nitric oxide- and cytokine-induced β-cell death. For this purpose, isolated human islets were treated with d-siRNA (diced small interfering RNA) and then exposed to the nitr...

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Bibliografiske detaljer
Main Authors: Makeeva, Natalia, Myers, Jason W., Welsh, Nils
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383671/
https://ncbi.nlm.nih.gov/pubmed/16097952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050814
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