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Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer

TP53 is universally recognized as a pivotal protein in cell-cycle fate and apoptotic induction and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer. Recently, the kinase MKK3 emerged as a potential therapeutic target in different types of solid tumor being linked...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Stramucci, Lorenzo, Pranteda, Angelina, Bossi, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977104/
https://ncbi.nlm.nih.gov/pubmed/29751559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10050131
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