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Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer

MKK3 is a member of the dual specificity kinase group specific upstream activator of p38 MAPK proteins. We originally identified MKK3 as mutant p53 (mutp53) gain-of-function (GOF) upregulated target gene in different tumor models. To deeply investigate the MKK3 functions in cancer, taking advantage...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Stramucci, Lorenzo, Bossi, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935053/
https://ncbi.nlm.nih.gov/pubmed/31881903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1513-4
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