Loading...

Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer

MKK3 is a member of the dual specificity kinase group specific upstream activator of p38 MAPK proteins. We originally identified MKK3 as mutant p53 (mutp53) gain-of-function (GOF) upregulated target gene in different tumor models. To deeply investigate the MKK3 functions in cancer, taking advantage...

Full description

Saved in:
Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Stramucci, Lorenzo, Bossi, Gianluca
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935053/
https://ncbi.nlm.nih.gov/pubmed/31881903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1513-4
Tags: Add Tag
No Tags, Be the first to tag this record!