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The structure of a protein primer–polymerase complex in the initiation of genome replication

Picornavirus RNA replication is initiated by the covalent attachment of a UMP molecule to the hydroxyl group of a tyrosine in the terminal protein VPg. This reaction is carried out by the viral RNA-dependent RNA polymerase (3D). Here, we report the X-ray structure of two complexes between foot-and-m...

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Detalhes bibliográficos
Main Authors: Ferrer-Orta, Cristina, Arias, Armando, Agudo, Rubén, Pérez-Luque, Rosa, Escarmís, Cristina, Domingo, Esteban, Verdaguer, Nuria
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383552/
https://ncbi.nlm.nih.gov/pubmed/16456546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600971
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