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The structure of a protein primer–polymerase complex in the initiation of genome replication
Picornavirus RNA replication is initiated by the covalent attachment of a UMP molecule to the hydroxyl group of a tyrosine in the terminal protein VPg. This reaction is carried out by the viral RNA-dependent RNA polymerase (3D). Here, we report the X-ray structure of two complexes between foot-and-m...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383552/ https://ncbi.nlm.nih.gov/pubmed/16456546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600971 |
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