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Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins
BACKGROUND: The premature aging and cancer-prone Werner and Bloom syndromes are caused by defects in the RecQ helicase enzymes WRN and BLM, respectively. Recently, both WRN and BLM (as well as several other RecQ members) have been shown to possess a strand annealing activity in addition to the requi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1382243/ https://ncbi.nlm.nih.gov/pubmed/16412221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-7-1 |
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