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Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins

BACKGROUND: The premature aging and cancer-prone Werner and Bloom syndromes are caused by defects in the RecQ helicase enzymes WRN and BLM, respectively. Recently, both WRN and BLM (as well as several other RecQ members) have been shown to possess a strand annealing activity in addition to the requi...

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Detalhes bibliográficos
Main Authors: Machwe, Amrita, Lozada, Enerlyn M, Xiao, Liren, Orren, David K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382243/
https://ncbi.nlm.nih.gov/pubmed/16412221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-7-1
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