Rearrangement of a 1,3-trans-{Pt(NH(3))(2)[(GXG)-N7G,N7G]} intrastrand cross-link into interstrand cross-links within RNA duplexes
The cross-linking reaction described previously in the DNA and 2′-O-methyl RNA series is extended to RNA duplexes. A 17mer single-stranded RNA containing the 1,3-trans-{Pt(NH(3))(2)[(GAG)-N7G,N7G]} intrastrand chelate, named G*AG* (* indicating a platinated base) gives, upon pairing with the complem...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137981/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12466547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf672 |
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