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Rearrangement of a 1,3-trans-{Pt(NH(3))(2)[(GXG)-N7G,N7G]} intrastrand cross-link into interstrand cross-links within RNA duplexes

The cross-linking reaction described previously in the DNA and 2′-O-methyl RNA series is extended to RNA duplexes. A 17mer single-stranded RNA containing the 1,3-trans-{Pt(NH(3))(2)[(GAG)-N7G,N7G]} intrastrand chelate, named G*AG* (* indicating a platinated base) gives, upon pairing with the complem...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Escaffre, Marine, Chottard, Jean-Claude, Bombard, Sophie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12466547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf672
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