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‘Immunomers’—novel 3′–3′-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents

Oligodeoxyribonucleotides containing CpG dinucleotides (CpG DNAs) are currently being evaluated as novel immunomodulators in clinical trials. Recently, we showed that an accessible 5′ end is required for immunostimulatory activity and blocking the 5′ end of CpG DNA by conjugation of certain ligands...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Yu, Dong, Kandimalla, Ekambar R., Bhagat, Lakshmi, Tang, Jin-Yan, Cong, Yanping, Tang, Jimmy, Agrawal, Sudhir
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137145/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384593/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf582
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