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‘Immunomers’—novel 3′–3′-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents

Oligodeoxyribonucleotides containing CpG dinucleotides (CpG DNAs) are currently being evaluated as novel immunomodulators in clinical trials. Recently, we showed that an accessible 5′ end is required for immunostimulatory activity and blocking the 5′ end of CpG DNA by conjugation of certain ligands...

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Detalhes bibliográficos
Main Authors: Yu, Dong, Kandimalla, Ekambar R., Bhagat, Lakshmi, Tang, Jin-Yan, Cong, Yanping, Tang, Jimmy, Agrawal, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137145/
https://ncbi.nlm.nih.gov/pubmed/12384593
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