‘Immunomers’—novel 3′–3′-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents
Oligodeoxyribonucleotides containing CpG dinucleotides (CpG DNAs) are currently being evaluated as novel immunomodulators in clinical trials. Recently, we showed that an accessible 5′ end is required for immunostimulatory activity and blocking the 5′ end of CpG DNA by conjugation of certain ligands...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384593/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf582 |
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