‘Immunomers’—novel 3′–3′-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents

Oligodeoxyribonucleotides containing CpG dinucleotides (CpG DNAs) are currently being evaluated as novel immunomodulators in clinical trials. Recently, we showed that an accessible 5′ end is required for immunostimulatory activity and blocking the 5′ end of CpG DNA by conjugation of certain ligands...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Yu, Dong, Kandimalla, Ekambar R., Bhagat, Lakshmi, Tang, Jin-Yan, Cong, Yanping, Tang, Jimmy, Agrawal, Sudhir
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2002
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384593/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf582
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