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The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity

Ribosomal variants carrying mutations in active site nucleotides are severely compromised in their ability to catalyze peptide bond formation (PT) with minimal aminoacyl tRNA substrates such as puromycin. However, catalysis of PT by these same ribosomes with intact aminoacyl tRNA substrates is uncom...

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Bibliografische gegevens
Hoofdauteurs: BRUNELLE, JULIE L., YOUNGMAN, ELAINE M., SHARMA, DIVYA, GREEN, RACHEL
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Copyright 2006 by RNA Society 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370883/
https://ncbi.nlm.nih.gov/pubmed/16373492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2256706
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